Central Cardiovascular Regulation Group
Research Interests |
Key Findings |
Techniques |
Prospective Students |
Recent Publications
2008
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Allen AM, O’Callaghan EL, Hazelwood L, Germain S, Castrop H, Schnermann J, Bassi J. Distribution of cells expressing human renin promoter activity in the brain of a transgenic mouse. Brain Res. 2008 (in press)
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Sevigny CP, Bassi J, Teschemacher AG, Kim K-S, Williams DA , Anderson CR, Allen AM. C1 Neurons in the Rat Rostral Ventrolateral Medulla Differentially Express Vesicular Monoamine Transporter 2 in Soma and Axonal Compartments. Eur. J. Neurosci. 2008; 28: 1536-1544.
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Stefanidis A, Verty ANA, Allen AM, Owens NC, Cowley MC, Oldfield BJ. The role of thermogenesis in antipsychotic drug induced weight gain. Obesity 2008 (in press).
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Ryall JG, Schertzer JD, Allen AM, Lynch GS. Chronic β2-agonist administration impairs cardiac relaxation via reduced SR Ca2+-ATPase activity. Am. J. Physiol. (Heart) 2008; 294: H2587-H2595.
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Verty ANA, Allen AM, Oldfield BJ. The effect of the cannabinoid receptor antagonist SR 141716 (rimonabant) on energy expenditure. Obesity 2008 (in press).
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McKinley MJ, Walker LL, Alexiou T, Allen AM, Campbell DJ, DiNicolantonio R, Oldfield BJ, Denton DA. Osmoregulatory fluid intake but not hypovolemic thirst is intact in mice lacking angiotensin. Am. J. Physiol. 2008; 294: R1533-R1543
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Allen AM, O’Callaghan EL, Chen D, Bassi JK. Central neural regulation of cardiovascular function by angiotensin- a focus on the rostral ventrolateral medulla. J. Neuroendocrinol. 2008 (in press)
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Allen, AM, Chai SY and Mendelsohn FAO. Neuronal Angiotensin, in. L. Squire, T. Albright, F. Bloom, F. Gage, N. Spitzer (eds): The New Encyclopedia of Neuroscience 2008 (in press).
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McKinley, MJ, Allen AM, Oldfield BJ. Angiotensin actions on and within the brain. in. L. Squire, T. Albright, F. Bloom, F. Gage, N. Spitzer (eds): The New Encyclopedia of Neuroscience 2008 (in press)
2007
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Oldfield BJ, Allen AM, Davern P, Giles ME, Owens N. Lateral hypothalamic “command neurons” with axonal projections to regions involved in both feeding and thermogenesis. Eur. J. Neurosci. 2007; 25: 2404-2412.
2006
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Steinberg GR, Watt MJ, Fam BC, Proietto J, Andrikopoulos S, Allen AM. Cillary neurotrophic factor supresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology. 2006; 147(8):3906-14.
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Allen AM, Dosanjh J, Erac M, Dassanayake S, Hannan RD, Thomas WG. Expression of constiutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure. Hypertension 2006; 47(6):1054-61.
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Allen AM, Dosanjh J, Dassanayake S, Tan G, Thomas WG. Baroreceptor reflex stimulation does not induce cytomegalovirus promoter-driven transgene expression in the ventrolateral medulla in vivo. Auton. Neurosci. 2006; 126-127:150-5.
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Richardson RJ, Grkovic I, Allen AM, Anderson CR. Separate neurochemical classes of sympathetic postganglionic neurons project to the ventricle of the rat heart. Cell Tissue Res. 2006; 324(1):9-16.
Current funding.
NH&MRC
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2007-2009- Respiratory modulation of RVLM premotor neurons: role in the sympathetic over-activity of hypertension. A.M. Allen, J.F.R. Paton, A.E. Pickering, $324,000.
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2009-2011- Regulation of sympathetic vasomotor function by brain angiotensin: cell-specific modulation of function in vivo. A.M. Allen, W.G. Thomas. $341,250.
National Heart Foundation
- 2008-2009- Modulation of sympathetic vasomotor tone in pre-hypertensive rats: Understanding the role of locally formed angiotensin II in the brain. A.M. Allen $129,000.