Enteric Neuroscience Laboratory
Welcome to our homepage!
The Enteric Neuroscience Laboratory (ENL), headed by Joel C Bornstein, is primarily concerned with the neurophysiology of the gastrointestinal tract.
Our lab is part of the Neuroscience Group in the Physiology Department.
Students who are interested in undertaking a project with Prof. Joel Bornstein or Dr Kulmira Nurgali are encouraged to email them directly. Prospective Honours students are encouraged to read the Physiology Honours Information Booklet for 2008.
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Current projects undertaken in the lab include:
- The effect of enterotoxins on gut motility and secretion
- Characterisation of fed-state motility patterns
- Synaptic transmission and transmitters in the enteric nervous system
- Nociceptive transmission from the gastrointestinal tract
- Development of enteric motility patterns
- Effects of intestinal inflammation on the enteric nervous system
- Modelling enteric reflex circuits
Experimental techniques used by the ENL:
- Intracellular recording
- Extracellular recording
- Video imaging and mathematical analysis
- Whole organ pharmacology
- Immunohistochemistry
- Retrograde labelling
- Mathematical and computational modelling