Enteric Neuroscience Laboratory
Welcome to our homepage!
The Enteric Neuroscience Laboratory (ENL), headed by Joel C Bornstein, is primarily concerned with the neurophysiology of the gastrointestinal tract.
Our lab is part of the Neuroscience Group in the Physiology Department.
Students who are interested in undertaking a project with Prof. Joel Bornstein or Dr Kulmira Nurgali are encouraged to email them directly. Prospective Honours students are encouraged to read the Physiology Honours Information Booklet for 2008.
Current projects undertaken in the lab include:
- The effect of enterotoxins on gut motility and secretion
- Characterisation of fed-state motility patterns
- Synaptic transmission and transmitters in the enteric nervous system
- Nociceptive transmission from the gastrointestinal tract
- Development of enteric motility patterns
- Effects of intestinal inflammation on the enteric nervous system
- Modelling enteric reflex circuits
Experimental techniques used by the ENL:
- Intracellular recording
- Extracellular recording
- Video imaging and mathematical analysis
- Whole organ pharmacology
- Retrograde labelling
- Mathematical and computational modelling