Profile
I completed my Bachelor of Biological Science (with Honours) in 2000, followed by my PhD in Zoology (supervised by Professor DG. Stephenson) at La Trobe University. My PhD thesis was entitled "a study of skeletal muscle function alteration at elevated physiological temperatures".
I began postodoctoral training at Melbourne University under Prof GS. Lynch in 2006 where I am researching the effects of ageing and disease states on skeletal muscle regeneration and function.
Teaching
Guest lecturer and practical class supervisor for 3rd year Physiology, 308 (Melbourne University)
Service to the University, discipline
or community and recent presentations
Member of the
- Australian Physiological Society (AuPS)
- Biophysical Society (BPS)
- American Physiological Society (APS)
Research
Profile, Interests and Recent Publications
Skeletal muscle function
Recent Publications:
van der Poel C, Edwards JN, Macdonald WA & Stephenson DG. Mitochondrial superoxide (O2˙-) production in skeletal muscle fibers of the rat and decreased fiber excitability. Am J Physiol Cell Physiol. 292(4):C1353-60. 2007
van der Poel C, Stephenson DG. Effects of elevated physiological temperatures on sarcoplasmic reticulum function in mechanically skinned muscle fibers of the rat. Am J Physiol Cell Physiol. 293(1):C133-41. 2007
Edwards JN, Macdonald WA, van der Poel C & Stephenson DG. O2˙- production at 37 oC plays a critical role in depressing tetanic force of isolated rat and mouse skeletal muscle. Am J Physiol Cell Physiol. 293(2):C650-60. 2007
van der Poel C, Schertzer JD, Shavlakadze T, Grounds MD, Lynch GS. Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophic mdx mice. Am J Physiol Cell Physiol. 294(1):C161-8. 2008
van der Poel C, Edwards JN, Macdonald WA, Stephenson DG. Effect of temperature-induced reactive oxygen species production on excitation-contraction coupling in mammalian skeletal muscle. Clin Exp Pharmacol Physiol. 35(12):1482-7. 2008
Vlahovich N, Kee AJ, Van der Poel C, Kettle E, Hernandez-Deviez D, Lucas C, Lynch GS, Parton RG, Gunning PW, Hardeman EC. Cytoskeletal tropomyosin Tm5NM1 is required for normal excitation-contraction coupling in skeletal muscle. Mol Biol Cell. 20(1):400-9. 2009
Research
Funding
Funded by Roche.
Presentations
2006: AuPS conference
2007: FASEB meeting
2008: AAESS and AuPS conferences
Supervisor
Gordon Lynch
