Publications Report 2001
B1 - Chapters in Research Books
Cropper SJ. 2001. Local and Global Motion Signals and their interaction in space and time. In JM Zanker & J Zeil (eds), Motion Vision. Berlin, Germany: Springer Verlag, pp. 125-140.
Morgan TO, Griffiths CD & Delbridge LM. 2001. Wall stress, Angiotensin II, and Left Ventricular Hypertrophy. In L Epstein & HR Brunner (eds), Angiotensin II Receptor Antagonists. Pennsylvania, United States of America: Hanley and Belfus Inc, pp. 223-234.
C1 - Journal Articles - Refereed
Abro EU, Griffiths CD, Morgan TO & Delbridge LM. 2001. Regression of cardiac hypertrophy in the SHR by combined renin-angiotensin system blockade and dietary sodium restriction. Journal of the Renin-Angiotensin-Aldosterone System. 2:S148-S153.
Anderson MJ, Cotter D, Garnham P, Casley DJ & Febbraio MA. 2001. Effect of glycerol-induced hyperhydration on thermoregulation and metabolism during exercise in the heat. International Journal of Sport Nutrition and Exercise Metabolism. 11(3):315-333.
Angus DJ, Febbraio MA, Lasini D & Hargreaves M. 2001. Effect of carbohydrate ingestion on glucose kinetics during exercise in the heat. Journal of Applied Physiology. 90(2):601-605.
Blair-West JR, Carey KD, Denton DA, Madden LJ, Weisinger RS & Shade R. 2001. Possible contribution of brain angiotensin III to ingestive behaviors in baboons. American Journal of Physiology - Regulatory Integrative Comparative Physiology. 281:R1633-R1636.
Campbell SE, Angus DJ & Febbraio MA. 2001. Glucose kinetics and exercise performance during phases of the menstrual cycle: effect of glucose ingestion. American Journal of Physiology - Endocrinology and Metabolism. 281:E817-E825.
Campbell SE & Febbraio MA. 2001. Effect of ovarian hormones on mitochondrial enzyme activity in the fat oxidation pathway of skeletal muscle. American Journal of Physiology - Endocrinology and Metabolism. 281:E803-E808.
Campbell SE & Febbraio MA. 2001. Effects of ovarian hormones on exercise metabolism. Current Opinion in Clinical Nutrition and Metabolic Care. 4:515-520.
Cotter D, Sleivert GG, Roberts WS & Febbraio MA. 2001. Effect of pre-cooling, with and without thigh cooling, on strain and endurance exercise performance in the heat. Comparative Biochemistry and Physiology A - Molecular and Integrative Physiology. 128:667-677.
Cropper SJ & Johnston A. 2001. Motion of contrast envelopes: peace and noise. Journal of the Optical Society of America A -Optics Image Science and Vision. 18(9):2237-2254.
Deague J, Wilson M, Harrap SB & Grigg L. 2001. Physiological relationships between central vascular haemodynamics and left ventricular structure. Clinical Science. 101:79-85.
Ellis JA & Harrap SB. 2001. The Genetics of Androgenetic Alopecia. Clinics in Dermatology. 19:149-154.
Ellis JA, Stebbing MJ & Harrap SB. 2001. Male pattern bladness is not associated with established cardiovascular risk factors in the general population. Clinical Science. 100:401-404.
Ellis JA, Stebbing MJ & Harrap SB. 2001. Polymorphism of the Androgen Receptor Gene is associated with Male Pattern Baldness. Journal of Investigative Dermatology. 116(3):452-455.
Ellis JA, Stebbing MJ & Harrap SB. 2001. Significant population variation in adult male height associated with the Y Chromosome and the Aromatase Gene. Journal of Clinical Endocrinology & Metabolism. 86(9):4147-4150.
Ellis JA, Wong ZYH, Stebbing MJ & Harrap SB. 2001. Sex, Genes and blood pressure. Clinical and Experimental Pharmacology and Physiology. 28:1053-1055.
Faux CH, Turnley AM, Epa W, Cappai R & Bartlett P. 2001. Interactions between Fibroblast Growth Factors and Notch Regulate Neuronal Differentiation. Journal of Neuroscience. 21(15):5587-5596.
Febbraio MA. 2001. Alterations in energy metabolism during exercise and heat stress. Sports Medicine. 31(1):47-59.
Finn JP, Ebert TR, Withers RT, Carey MF, Phillips JW & Febbraio MA. 2001. Effect of creatine supplementation on metabolism and performance in humans during intermittent sprint cycling. European Journal of Applied Physiology. 84:238-243.
Frueh BR, Gregorevic P, Williams DA & Lynch GS. 2001. Specific force of the rat extraocular muscles, levator and superior rectus, measured in situ. Journal of Neurophysiology. 85:1027-1032.
Gilbert RE, Wilkinson-Berka JLA & Kelly DJ. 2001. Angiotensin and Renal Fibrosis. Contributions to Nephrology. 135:171-186.
Gregorevic P, Lynch GS & Williams DA. 2001. Hyperbaric oxygen modules antioxidant enzyme activity in rat skeletal muscles. European Journal of Applied Physiology. 86:24-27.
Griffiths CD, Morgan TO & Delbridge LM. 2001. Effects of combined administration of ACE inhibitor and angiotensin II receptor antagonist are prevented by a high NaCl intake. Journal of Hypertension. 19(11):2087-2095.
Gu BJ, Zhang W, Worthington RA, Sluyter R, Dao-Ung P, Petrou S, Barden JA & Wiley JS. 2001. A Glu-496 to Ala Polymorphism leads to loss of function of the Human P2X7 Receptor. Journal of Biological Chemistry. 276(14):11135-11142.
Harrap SB & Petrou S. 2001. Utility of genetic approaches to common cardiovascular diseases. American Journal of Physiology - Heart and Circulatory Physiology. 281:H1-H6.
Jacobson TL, Febbraio MA, Arkinstall MJ & Hawley JA. 2001. Effect of caffeine co-ingested with carbohydrate or fat on metabolism and performance in endurance-trained men. Experimental Physiology. 86:137-144.
Kapsa RMI, Quigley AF, Lynch GS, Steeper K, Kornberg AJ, Gregorevic P, Austin L & Byrne E. 2001. In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement. Human Gene Therapy. 12(6):629-642.
Lomax AEG, Bertrand PP & Furness JB. 2001. Electrophysiological Characteristics Distinguish Three Classes of Neuron in Submucosal Ganglia of the Guinea-Pig Distal Colon. Neuroscience. 103(1):245-255.
Lowry S, Murray SS, Coulson EJ, Epa W, Bartlett PF, Barrett GL & Cheema SS. 2001. Systemic administration of antisense p75NTR oligodeoxynucleotides rescues axotomised spinal motor neurons. Journal of Neuroscience Research. 64:11-17.
Lynch GS, Cuffe SA, Plant DR & Gregorevic P. 2001. IGF-I treatment improves the functional properties of fast- and slow-twitch skeletal muscles from dystrophic mice. Neuromuscular Disorders. 11:260-268.
Lynch GS, Hinkle RT, Chamberlain JS, Brooks SV, Faulkner J & Faulkner JA. 2001. Force and power output of fast and slow skeletal muscles from mdx mice 6-28 months old. Journal of Physiology - London. 535(2):591-600.
Lynch GS, Hinkle RT & Faulkner JA. 2001. Force and power output of diaphragm muscle strips from mdx and control mice after clenbuterol treatment. Neuromuscular Disorders. 11:192-196.
Maric C, Casley DJ, Harris PJ & Alcorn DG. 2001. Angiotensin II Binding to Renomedullary Interstitial Cells is Regulated by Osmolality. Journal of the American Society of Nephrology. 12:450-455.
Mifsud SA, Allen TJ, Bertram JF, Hulthen UL, Kelly DJ, Cooper ME, Wilkinson-Berka JLA & Gilbert RE. 2001. Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade. Diabetologia. 44:878-882.
Morgan TO. 2001. Effect of combining angiotensin receptor blockers and ACE inhibitors on cardiovascular disease. Journal of the Renin-Angiotensin-Aldosterone System. 2:S223-S226.
Morgan TO. 2001. Interactions between sodium and angiotensin. Clinical and Experimental Pharmacology and Physiology. 28(12):1070-1073.
Morgan TO, Anderson AIE & MacInnis RJ. 2001. ACE inhibitors, beta-blockers, calcium blockers, and diuretics for the control of Systolic Hypertension. American Journal of Hypertension. 14:241-247.
Morgan TO, Aubert JF & Brunner HR. 2001. Interaction between sodium intake, angiotensin II, and blood pressure as a cause of Cardiac Hypertrophy. American Journal of Hypertension. 14:914-920.
Panchal R, Williams DA, Kitchener P, Reilly AM, Bowser DN & Petrou S. 2001. Gene Transfer: Manipulating and Monitoring Function in Cells and Tissues. Clinical and Experimental Pharmacology and Physiology. 28:687-691.
Plant DR, Gregorevic P, Williams DA & Lynch GS. 2001. Redox modulation of maximum force production of fast- and slow-twitch skeletal muscles of rats and mice. Journal of Applied Physiology. 90:832-838.
Plant DR & Lynch GS. 2001. Rigor force responses of permeabilized fibres from fast and slow skeletal muscles of aged rats. Clinical and Experimental Pharmacology and Physiology. 28:779-781.
Reilly AM, Petrou S, Panchal R & Williams DA. 2001. Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts. Cell Calcium. 30(1):59-66.
Rong P, Wilkinson-Berka JLA & Skinner SL. 2001. Control of renin secretion from adrenal gland in transgenic Ren-2 and normal rats. Molecular and Cellular Endocrinology. 173:203-212.
Saunders P, Watt MJ, Garnham P, Spriet LL, Hargreaves M & Febbraio MA. 2001. No effect of mild heat stress on the regulation of carbohydrate metabolism at the onset of exercise. Journal of Applied Physiology. 91(5):2282-2288.
Slievert GG, Cotter JD, Roberts WS & Febbraio MA. 2001. The influence of whole-body vs torso pre-cooling on physiological strain and performance of high-intensity exercise in the heat. Comparative Biochemistry and Physiology A - Molecular and Integrative Physiology. 128:657-666.
Small DH, Mok SS & Bornstein JC. 2001. Alzheimer's disease and A[beta] toxicity: from top to bottom. Nature Reviews Neuroscience. 2:595-598.
Starkie RL, Arkinstall MJ, Koukoulas I, Hawley JA & Febbraio MA. 2001. Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans. Journal of Physiology - London. 533:582-591.
Starkie RL, Rolland J, Angus DJ, Anderson MJ & Febbraio MA. 2001. Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-a levels after prolonged running. American Journal of Physiology - Cell Physiology. 280(4):C769-C774.
Starkie RL, Rolland J & Febbraio MA. 2001. Effect of adrenergic blockade on lymphocyte cytokine production at rest and during exercise. American Journal of Physiology - Cell Physiology. 281:C1233-C1240.
Stebbing MJ, Johnson PJ, Vremec MA & Bornstein JC. 2001. Role of a2-adrenoceptors in the sympathetic inhibition of motility reflexes of guinea-pig ileum. Journal of Physiology - London. 534:465-478.
Steensberg A, Febbraio MA, Osada T, Schjerling P, Van Hall G, Saltin B & Klarlund Pedersen B. 2001. Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content. Journal of Physiology - London. 537(2):633-639.
Wallace R, Marini C, Petrou S, Harkin A, Bowser DN, Panchal R, Williams DA, Sutherland R, Mulley JC, Scheffer IE & Berkovic SF. 2001. Mutant GABAA receptor gamma2-subunit in childhood absence epilepsy and febrile seizures. Nature Genetics. 28(May):49-52.
Walsh RC, Koukoulas I, Garnham P, Moseley PL, Hargreaves M & Febbraio MA. 2001. Exercise increases serum Hsp72 in humans. Cell Stress and Chaperones. 6(4):386-393.
Watt MJ, Howlett KF, Febbraio MA, Spriet LL & Hargreaves M. 2001. Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans. Journal of Physiology - London. 534(1):269-278.
Wilkinson-Berka JLA, Gibbs NJ, Cooper ME, Skinner SL & Kelly DJ. 2001. Renoprotective and anti-hypertensive effects of combined valsartan and perindopril in progressive diabetic nephropathy in the transgenic (mRen-2)27 rat. Nephrology, Dialysis, Transplantation. 16:1343-1349.
Wilkinson-Berka JLA, Kelly DJ & Gilbert RE. 2001. The interaction between the Renin-Angiotensin System and Vascular Endothelial Growth Factor in the Pathogenesis of Retinal Neovascularization in Diabetes. Journal of Vascular Research. 38:527-535.
Wlodek ME, Koutsis K, Westcott KT, Ho P, Di Nicolantonio R & Moseley JM. 2001. The Spontanously Hypertensive Rat Fetus, Not the Mother, is Responsible for the Reduced Amniotic Fluid PTHrP Concentrations and Growth Restriction. Placenta. 22:646-651.
C6 - Review Articles
Delbridge LM. 2001. Angiotensin II: A proven therapeutic target with some mechanistic mysteries. Heart Lung and Circulation. 10:45-47.
Harrap SB & Hopper JL. 2001. Genetics of Haemostasis. Lancet. 357:83-84.
Lynch GS. 2001. Novel therapies for muscular dystrophy and other muscle wasting conditions. Expert Opinion on Therapeutic Patents. 11(4):587-601.
Lynch GS. 2001. Therapies for improving muscle function in neuromuscular disorders. Exercise and Sport Sciences Reviews. 29(4):141-148.
F1 - Conference Publications - Full written paper - refereed
Fritze PA, Kavnoudias H, Kemm RE & Williams NT. 2001. Developing a Collaborative Learning Environment in Physiology — Using Online Architecture to Link Faculty and Institution Needs. In CM Montgomerie & JV Viteli (eds), Proceedings of Ed-Media 2001 World Conference on Educational Multimedia, Hypermedia & Telecommunications . (2001) : 906-911. Virginia, United States of America: Association for the Advancement of Computing in Education (AACE).
Kemm RE, Williams NT, Fritze PA, Kavnoudias H & Stone PN. 2001. Learning of key scientific concepts in a web-based on-campus collaborative learning environment. In CM Montgomerie & JV Viteli (eds), Proceedings of Ed-Media 2001 World Conference on Educational Multimedia, Hypermedia & Telecommunications. (2001) : 914-919. Virginia, United States of America: Association for the Advancement of Computing in Education (AACE).
Kemm RE, Williams NT, Kavnoudias H, Fritze PA & Weaver-Cowdroy DA. 2001. Collaborative learning: on-campus in a technology based environment. In NS Smythe (ed), e-Xplore 2001: a face-to-face odyssey (Apple University Consortium Academic and Developers Conference). (2001) : 7.1-7.14. Sydney, Australia: Apple Computer Australia.
Weaver-Cowdroy DA, Kemm RE, Gilding T, Petrovic T, Harris PJ & Delbridge LM. 2001. Evolution of a student model building program designed to assist understanding of Biological Control Systems. In CM Montgomerie & JV Viteli (eds), Proceedings of Ed-Media 2001 World Conference on Educational Multimedia, Hypermedia & Telecommunications. 2009-2010. Virginia, United States of America: Association for the Advancement of Computing in Education (AACE).
Q8 - Research in Progress (RIP)
Alcorn DG, Maric C & Harris PJ. 2001. Mechanisms of osmotic regulation in vasoactive peptide receptors in rat kidney.
Bertrand PP. 2001. Sensory transduction mechanisms from the mucosa to the intrinsic sensory neurones of the intestine.
Bornstein JC, Davies PJ, Monro R, Thornton PDJ & Gwynne RM. 2001. Synaptic transmission in the enteric nervous system.
Gwynne RM, Bornstein JC, Bertrand PP & Monro R. 2001. Motor patterns in the small intestine.
Lynch GS. 2001. IGF-I treatment for improving muscle function in muscular dystrophy.
Lynch GS & Williams DA. 2001. Mechanisms of injury, regeneration and plasticity of skeletal muscle.
Sillence M & Lynch GS. 2001. Developing a rational approach to the use of anabolic compounds in treating muscle wasting disorders.
Thomas DM, Kelly DJ, Moseley JM & Holding NL. 2001. Role of PTHrP in neu-mediated breast cancer.
Thomas EA, Bornstein JC & Sjovall H. 2001. Modelling the enteric nervous system.
Wilkinson-Berka JLA & Cooper ME. 2001. The role of renin-angiotensin and growth factors in developmental and pathological neovascularisation in the retina.
Woods MG, Lynch GS & Wiesenfeld D. 2001. Structure and function of human mandibular muscles in subjects with different underlying vertical facial patterns.
Q9 - Substantial Grants Received
Barrett GL. 2001. To develop a computer aided learning module for long term potentiation in the nervous system. Melbourne University, Faculty IT Grant.
Bertrand PP. 2001. Electrochemical recording apparatus for detection of serotonin release from individual intestinal enterochromaffin cells. ANZ, Medical Research & Technology Grant.
Bornstein JC. 2001. Analysis of the functions of neurons within the intestine using computer simulation of large scale anatomically realistic enteric neural circuits. Melbourne University, Melbourne Research Development Grant.
Bornstein JC & Davies PJ. 2001. Correlation of the electrophysiological morphological and neurochemical properties of intestinal neurons. Clive & Vera Ramaciotti Foundation, Research Grant.
Di Nicolantonio R & Delbridge LM. 2001. To develop a computer aided learning module for acid base balance. Melbourne University, Faculty IT Grant.
Febbraio MA. 2001. Effect of glucose availability on interleukin-6 production during exercise in humans. Melbourne University, Collaborative Research Program.
Febbraio MA. 2001. Effects of prolonged exercise and glycogen availability on heat shock protein production in contracting human skeletal muscle. Melbourne University, Melbourne Research Development Grant.
Harrap SB. 2001. Oocyte Patch and Voltage Clamp Unit for the Victorian Physiological Genomics Centre. Clive & Vera Ramaciotti Foundation, Major Equipment Grant.
Kemm RE, Dantas AM & Weaver D. 2001. Interactive virtual experimentation in science and medicine: cardiovascular compensation and circulatory shock. Melbourne University, TalMET.
Kemm RE, Kavnoudias H, Williams NT, Fritze PA & Wlodek ME. 2001. Use of web based pedagogical elements with an online course architecture to enhance student integration of knowledge derived from different but related principles. Melbourne University, TalMET.
Lynch GS & Kapsa RMI. 2001. Dystrophin gene repair in mdx mouse myoblasts and bone marrow cells as a basis for autologous transplant in human DMD. NH&MRC, NH&MRC Grant.
Wilkinson-Berka JLA. 2001. New and improved therapies for the treatment of diabetic nephropathy and retinopathy: the role of growth factors. Rebecca L Cooper Medical Research Foundation Ltd, Research Grant.
Wilkinson-Berka JLA. 2001. New strategies for the prevention of severe diabetic nephropathy: the effect of tranilast in the transgenic Ren-2 rat. Eli Lilly Australia Pty Ltd, Endocrinology Research Grant.
Williams DA & Petrou S. 2001. Biosensors for Adenosine Triphosphate (ATP) based on modifications of green fluorescent protein (GFP). ARC, Biological Sciences.
Wlodek ME. 2001. Effects of placental insufficiency on fetal growth and cardiovascular PTHrP. Melbourne University, Melbourne Research Development Grant Scheme.
Wlodek ME, Kavnoudias H, Kennedy GE & Keppell MJ. 2001. A Woman's Reproductive Life Cycle. Melbourne University, TaL(M&ET).
R11 - Thesis Passed for Higher Degrees
Aldred KL. 2001. Phenotypic characterisation of hypertension genes.
Bian X. 2001. The transmission to and from motor neurons in the gastrointestinal tract.
Campbell SE. 2001. Effects of the ovarian hormones on energy metabolism.
Gregorevic P. 2001. Aspects of skeletal muscle regeneration and adaptation.
Starkie RL. 2001. The cytokine response to physical stress.
Trongtorsak P. 2001. Cardiomyocyte contractility and pH regulation in cardiac hypertrophy.
R12 - Thesis in Progress for Higher Degrees
Anderson MJ. 2001. Effect of ACE gene polymorphism on skeletal muscle metabolism in response to physical exercise and training.
Danes VR. 2001. Cardiomyocyte function and pH regulation.
Dantas AM. 2001. Cellular mechanism of actions of peptide hormones in the kidney.
De Gooyer TE. 2001. Characterisation of the rat ovarian renin-angiotensin system: transgenic and interventional studies.
De Lima J. 2001. Mechanisms of P75 Mediated Neuronal Apoptosis.
Domenighetti AAM. 2001. Characterization of mechanisms of cardiac remodeling in transgenic models of cardiac hypertrophy.
Mifsud SA. 2001. The pathogenesis of diabetic and hypertensive nephropathy: interventional studies in the transgenic m(Ren-2)27 rat.
Monro R. 2001. Calcium channel subtypes involved in Neurotransmitter release in the Enteric Nervous System.
Moravski CJ. 2001. The role of renin-angiotensin system and vascular endothelial growth factor in retinal and iris neovascularization.
Ping SE. 2001. Oestrogen: a trophic factor in cholinergic basal forebrain neurons.
Sarlos S. 2001. Involvement of the renin-angiostensin system and related growth factors in angiogenesis: studies in developing retina and diabetic ocular pathologies.
Smart ML. 2001. Molecular basis of P2X7 pore formation.
Stupka N. 2001. Contraction-induced injury in DMD.
Thomas EA. 2001. Mathematical and computer modelling of the enteric nervous system.
Thornton PDJ. 2001. Analysis of the enteric nervous system in control of intestinal motility.