Publications Report 2002
B1 - Chapters in Research Books
Bornstein JC, Furness JB, Kunze WAA & Bertrand PP. 2002. Enteric reflexes that influence motility. In S Brookes & M Costa (eds), Innervation of the Gastrointestinal Tract. London, United Kingdom: Taylor & Francis Ltd, pp. 1-56.
Lynch GS. 2002. Beta-2 Agonists. In M Bahrke & C Yesalis (eds), Performance Enhancing Substances in Sport and Exercise. Illinois, United States of America: Human Kinetics, pp. 47-64.
McKenzie JS, Chai S-Y, Giles ME & McKinley MJ. 2002. Dopaminergic System in the Basal Ganglia of Sheep. In LFB Nicholson & RLM Faull (eds), The Basal Ganglia VII. New York, United States of America: Kluwer Academic/Plenum Publishers, pp. 107-116.
C1 - Journal Articles - Refereed
Angus DJ, Febbraio MA & Hargreaves M. 2002. Plasma glucose kinetics during prolonged exercise in trained humans when fed carbohydrate. American Journal of Physiology - Endocrinology and Metabolism. 283:E573-E577.
Bennell KL, Khan K, Warmington SA, Forwood MR, Coleman BD, Bennett MB & Wark JD. 2002. Age does not influence the bone response to treadmill exercise in female rats. Medicine and Science in Sports and Exercise. 34(12):1958-1965.
Bertrand PP & Bornstein JC. 2002. ATP as a Putative Sensory Mediator: Activation of intrinsic sensory neurons of the Myenteric Plexus via P2X Receptors. Journal of Neuroscience. 22(12):4767-4775.
Bowser DN, Petrou S, Panchal R, Smart ML & Williams DA. 2002. Release of mitochondrial Ca2+ via the permeability transition activates endoplasmic reticulum Ca2+ uptake1. FASEB Journal. 16:1105-1107.
Bowser DN, Wagner A, Czajkowski C, Cromer A, Parker W, Wallace H, Harkin A, Mulley C, Marini C, Berkovic SF, Williams DA, Jones V & Petrou S. 2002. Altered kinetics and benzodiazepine sensitivity of a GABA-a receptor subunit mutation [akpha-2 (R43Q)] found in human epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 99(23):15170-15175.
Campbell SE & Febbraio MA. 2002. Effect of the ovarian hormones on GLUT4 expression and contraction-stimulated glucose uptake. American Journal of Physiology - Endocrinology and Metabolism. 282:E1139-E1146.
Clarke AL, Petrou S, Walsh Jr JV & Singer JJ. 2002. Modulation of BKCa channel activity by fatty acids: structural requirements and mechanism of action. American Journal of Physiology - Cell Physiology. 283:C1441-C1453.
Cui J, Hopper JL & Harrap SB. 2002. Genes and Family Environment Explain Correlations Between Blood Pressure and Body Mass Index. Hypertension. 40(July):7-12.
Delbridge LM, Kabbara AAH, Bellair CJ, Allman B, Nassis L, Roberts A & Nugent KA. 2002. Quantitative Phase Imaging - a new way to 'see' cells. Today's Life Science. 14(2):28-32.
Doolan GK, Panchal R, Fonnes EL, Clarke AL, Williams DA & Petrou S. 2002. Fatty acid augmentation of the cardiac slowly activating delayed rectifier current (IKs) is conferred by hminK1. FASEB Journal. 16(12):1662-1664.
Febbraio MA, Ott P, Nielsen HB, Steensberg A, Keller C, Krustrup P, Secher NH & Pedersen BK. 2002. Exercise induces hepatosplanchnic release of heat shock protein 72 in humans. Journal of Physiology - London. 544(3):957-962.
Febbraio MA & Pedersen BK. 2002. Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB Journal. 16:1335-1347.
Febbraio MA, Steensberg A, Walsh RC, Koukoulas I, Van Hall G, Saltin B & Klarlund Pedersen B. 2002. Reduced glycogen availability is associated with an elevation in HSP72 in contracting human skeletal muscle. Journal of Physiology - London. 538:911-917.
Greferath U, Mallard C, Roufail E, Rees SM, Barrett GL & Bartlett PF. 2002. Expression of the p75 neurotrophin receptor by striatal cholinergic neurons following global ischemia in rats is associated with neuronal degeneration. Neuroscience Letters. 332:57-60.
Gregorevic P, Plant DR, Leeding KS, Bach LA & Lynch GS. 2002. Improved contractile function of the mdx dystrophic mouse diaphragm muscle after insulin-like growth factor-1 administration. American Journal of Pathology. 161(6):2263-2272.
Gregorevic P, Williams DA & Lynch GS. 2002. Effects of Leukemia inhibitory factor on Rat Skeletal Muscles are modulated by Clenbuterol. Muscle & Nerve. 25:194-201.
Gregorevic P, Williams DA & Lynch GS. 2002. Hyperbaric oxygen increases the contractile function of regenerating rat slow muscles. Medicine and Science in Sports and Exercise. 34(4):630-636.
Harkins LA, Bowser DN, Dibbens L, Singh R, Phillips F, Wallace RH, Richards MC, Williams DA, Mulley JC, Berkovic SF, Scheffer IE & Petrou S. 2002. Truncation of the GABAA-Receptor γ2 Subunit in a Family with Generalized Epilepsy with Febrile Seizures Plus. American Journal of Human Genetics. 70:530-536.
Harrap SB, Danes VR, Ellis JA, Griffiths CD, Jones EF & Delbridge LM. 2002. The hypertrophic heart rat: a new normotensive model of genetic cardiac and cardiomyocyte hypertrophy. Physiological Genomics. 9:43-48.
Harrap SB, Wong ZYH, Stebbing M, Lamantia A & Bahlo M. 2002. Blood pressure QTLs identified by genome-wide linkage analysis and dependence on associated phenotypes. Physiological Genomics. 8:99-105.
Harrap SB, Zammit K, Wong ZYH, Williams FM, Bahlo M, Tonkin A & Anderson ST. 2002. Genome-Wide linkage Analysis of the Acute Coronary Syndrome suggests a Locus on Chromosome 2. Arteriosclerosis Thrombosis and Vascular Biology. 22:874-878.
Kelly DJ, Cox AJ, Tolcos M, Cooper ME, Wilkinson-Berka JLA & Gilbert RE. 2002. Attenuation of tubular apoptosis by blockade of the renin-angiotensin system in diabetic Ren-2rats. Kidney International. 61:31-39.
Kelly DJ, Wilkinson-Berka JLA, Ricardo SD, Cox AJ & Gilbert RE. 2002. Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mREN-2)27 rats. Nephrology Dialysis Transplantation. 17:985-991.
Maric C, Harris PJ & Alcorn DG. 2002. Changes in mean arterial pressure predict degranulation of renomedullary interstitial cells. Clinical and Experimental Pharmacology and Physiology. 29:1055-1059.
Mifsud SA, Skinner SL, Cooper ME, Kelly DJ & Wilkinson-Berka JLA. 2002. Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mren-2)27 rats. Journal of the American Society of Nephrology. 13:684-692.
Monro R, Bertrand PP & Bornstein JC. 2002. ATP and 5-HT are the principal neurotransmitters in the descending excitatory reflex pathway of the guinea-pig ileum. Neurogastroenterology and Motility. 14:255-264.
Morgan TO & Anderson A. 2002. A comparison of Candesartan, Felodipine, and their combination in the treatment of Elderly Patients with Systolic Hypertension. American Journal of Hypertension. 15:544-549.
Morgan TO & Anderson A. 2002. Low-dose combination therapy with Perindopril and Indapamide compared with Irbesartan. Clinical Drug Investigation. 22(8):553-560.
Morgan TO, Griffiths CD & Delbridge LM. 2002. Interaction of ACE inhibitors and AT1-receptor blockers on maximum blood pressure response in spontaneous hypertensive rats. Journal of the Renin-Angiotensin-Aldosterone System. 3(1):16-18.
Morgan TO, Griffiths CD & Delbridge LM. 2002. Low doses of Angiotensin Converting Enzyme Inhibitors and Angiotensin Type 1 Blockers have a synergistic effect but high doses are less than additive. American Journal of Hypertension. 15:1003-1005.
Panchal R, Smart ML, Bowser DN, Williams DA & Petrou S. 2002. Pore-Forming Proteins and their Application in Biotechnology. Current Pharmaceutical Biotechnology. 3:99-115.
Ping SE, Greferath U & Barrett GL. 2002. Estrogen treatment suppresses forebrain P75 Neurotrophin Receptor Expression in aged, noncycling female rats. Journal of Neuroscience Research. 69:51-60.
Plant DR & Lynch GS. 2002. Excitation-contraction coupling and sarcoplasmic reticulum function in mechanically skinned fibres from fast skeletal muscles of aged mice. Journal of Physiology - London. 543:169-176.
Plant DR, Lynch GS & Williams DA. 2002. Hydrogen peroxide increases depolarization-induced contraction of mechanically skinned slow twitch fibres from rat skeletal muscles. Journal of Physiology - London. 539:883-891.
Pritchard JE, Nowson CA, Billington T & Wark JD. 2002. Benefits of a year-long workplace weight loss program on cardiovascular risk factors. Nutrition and Dietetics. 59(2):87-96.
Ryall JG, Gregorevic P, Plant DR, Sillence MN & Lynch GS. 2002. Beta2-Agonist fenoterol has greater effects on the contractile function of rat skeletal muscles than clenbuterol. American Journal of Physiology - Regulatory Integrative Comparative Physiology. 283:R1386-R1394.
Shade R, Blair-West JR, Carey KE, Madden LJ, Weisinger HS & Denton DA. 2002. Synergy between angiotensin and aldosterone in evoking sodium appetite in baboons. American Journal of Physiology - Regulatory Integrative Comparative Physiology. 283:R1070-R1078.
Shade R, Blair-West JR, Carey KD, Madden LJ, Weisinger RS, Rivier JE, Vale WW & Denton DA. 2002. Ingestive responses to administration of stress hormones in baboons. American Journal of Physiology - Regulatory Integrative Comparative Physiology. 282:R10-R18.
Smart ML, Panchal R, Bowser DN, Williams DA & Petrou S. 2002. Pore formation is not associated with macroscopic redistribution of P2X7 receptors. American Journal of Physiology - Cell Physiology. 283:C77-C84.
Steensberg A, Keller C, Starkie RL, Osada T, Febbraio MA & Pedersen BK. 2002. Il-6 and TNF-α expression in, and release from, contracting human skeletal muscle. American Journal of Physiology - Endocrinology and Metabolism. 283:E1272-E1278.
Steensberg A, Van Hall G, Keller C, Osada T, Schjerling P, Pedersen BK, Saltin B & Febbraio MA. 2002. Muscle glycogen content and glucose uptake during exercise in humans: influence of prior exercise and dietary manipulation. Journal of Physiology - London. 541(1):273-281.
Thornton PDJ & Bornstein JC. 2002. Slow excitatory synaptic potentials evoked by distension in myenteric descending interneurones of guinea-pig ileum. Journal of Physiology - London. 539(2):589-602.
Toft AD, Jensen LB, Bruunsgaard H, Ibfelt T, Halkjaer-Kristensen J, Febbraio MA & Pedersen BK. 2002. Cytokine response to eccentric exercise in young and elderly humans. American Journal of Physiology - Cell Physiology. 283:C289-C295.
Wilkinson-Berka JLA, Kelly DJ, Koerner SM, Jaworski K, Davis B, Thallis V & Cooper ME. 2002. ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat. Diabetes. 51:3283-3289.
Wilkinson-Berka JLA, Kelly DJ, Rong P, Campbell DJ & Skinner SL. 2002. Characterisation of a thymic renin-angiotensin system in the transgenic m(Ren-2)27 rat. Molecular and Cellular Endocrinology. 194:201-209.
Worthington RA, Smart ML, Gu BJ, Williams DA, Petrou S, Wiley JS & Barden JS. 2002. Point mutations confer loss of ATP-induced human P2X7 receptor function. FEBS Letters. 512:43-46.
C2 - Unrefereed Journal Articles
Allman BE, Nassis L, Von Bibra M, Bellair CJ, Kabbara AAH, Barone-Nugent ED, Gaeth AP, Delbridge LM & Nugent KA. 2002. Optical Phase Microscopy: Quantitative Imaging and Conventional Phase Analogs. Microscopy and Analysis. 52:13-15.
Weaver DA, Kemm RE, Petrovic T, Harris PJ & Delbridge LM. 2002. Evolution of a Student Model-Building Program. Advances in Physiology Education. 26(4):288-298.
C3 - Unrefereed Letters or Notes
Ellis JA, Sinclair RD & Harrap SB. 2002. Androgenetic alopecia: pathogenesis and potential for therapy. Expert Reviews in Molecular Medicine. N/A:1-11.
Lynch GS. 2002. Novel therapies for sarcopenia: ameliorating age-related changes in skeletal muscle. Expert Opinion on Therapeutic Patents. 12(1):11-27.
C5 - Other Refereed Contributions to Refereed Journals
Morgan TO. 2002. Is non-dipping status a predictor of cardiac morbidity? Journal of Hypertension. 20:1469-1471.
Q8 - Research in Progress (RIP)
Bornstein JC, Gwynne RM, Davies PJ, Monro R & Heffer LF. 2002. Synaptic transmission in the enteric nervous system.
Bornstein JC, Gwynne RM & Sjovall H. 2002. Mechanisms responsible for nutrient-induced segmentation in the small intestine.
Bornstein JC, Hutson JM, Southwell B & Stanton M. 2002. Analysis of neuromuscular transmission in the colon of children with slow transit constipation.
Bornstein JC, Sjovall H, Thomas EA & Gwynne RM. 2002. Relationships between motility and secretion in the gastrointestinal tract.
Bornstein JC, Small DH & Jordan AK. 2002. Use of computational models to predict sites of neurotoxic action in Alzheimer's disease.
Bornstein JC, Thomas EA & Sjovall H. 2002. Modelling motor patterns in the gastrointestinal tract.
Delbridge LM, Di Nicolantonio R & Smyth G. 2002. Gene expression profiling in the hypertrophic heart.
Delbridge LM & Harrap SB. 2002. Angiotensin and spontaneous genetic cardiac hypertrophy.
Delbridge LM & Pedrazzini T. 2002. Cardiomyocyte structure and function in the angiotensinogen transgenic mouse.
Delbridge LM & Pepe S. 2002. Responses of hypertrophic cardiomyocytes to metabolic stresses.
Delbridge LM & Proietto J. 2002. Primary cardiac hypertrophy - a functional genetic approach to investigate mechanisms of metabolic remodelling.
Ellis JA. 2002. Genetic determinants of adult height in the general population.
Ellis JA. 2002. The role of the aromatase gene in male height.
Ellis JA, Abramson M & Matheson M. 2002. Genetic and environmental risk factors for respiratory disease.
Ellis JA & Harrap SB. 2002. The role of sex-steroid relates genes in cardiovascular risk.
Ellis JA, Harrap SB, Harrison S & Sinclair RD. 2002. The androgen receptor and female pattern baldness.
Ellis JA, Harrap SB & Wong ZYH. 2002. Linkage and sequence analysis of a locus on the X chromosome that contributes to population variation in blood pressure.
Fletcher EL & Wilkinson-Berka JLA. 2002. Neuro-glial dysfunction in diabetic retinopathy.
Haywood J, Shade R, Denton DA, Blair-West JR & Kammerer C. 2002. Angiotensin, sodium and genes in Primate Hypertension.
Lynch GS, Gregorevic P & Plant DR. 2002. Improving muscle function in muscular dystrophy.
Lynch GS, Gregorevic P & Plant DR. 2002. Mechanisms of age-related changes in skeletal muscle structure and function.
Lynch GS, Woods MG & Weisenfeld D. 2002. Human masseter muscle structure and function in subjects with different underlying vertical facial patterns.
Macheda ML, Williams ED, Best JD, Wlodek ME & Rogers SD. 2002. Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.
Rogers SD, Chandler J, Clarke AL, Petrou S & Best JD. 2002. Glucose transporter GLUT12: functional characterization in xenopus laevis oscytes.
Wilkinson-Berka JLA, De Gooyer TE & Stitt AW. 2002. Platelet derived growth factor and retinal angiogenesis.
Wilkinson-Berka JLA, Gilbert RE, Itescu S & Way KJ. 2002. Stem cell therapy and diabetic retinopathy.
Wilkinson-Berka JLA, Gilbert RE & Kelly DJ. 2002. Novel strategies to prevent diabetic microvascular complications.
Wilkinson-Berka JLA, Sharma K, Cooper ME & Jaworski K. 2002. The role of TGF-B in the development of diabetic nephropathy.
Wilkinson-Berka JLA, Werther G, Wraight CJ & Gilbert RE. 2002. Insulin-like growth factor and retinal angiogenesis.
Wlodek ME. 2002. A multimedia approach to A Woman's Reproductive Life Cycle.
Wlodek ME & Di Nicolantonio R. 2002. Role of the perinatal environment in experimental hypertension.
Wlodek ME & Moseley JM. 2002. Roles of PTHrP in placental and mammary function in models of perinatal growth restriction.
Wlodek ME & Rice GE. 2002. The roles of PTHrP and cytokines in human gestational tissues and fluids in normal and complicated pregnancies.
Wlodek ME & Wilkinson-Berka JLA. 2002. Role of renin in gestational and reproductive tissues.
Q9 - Substantial Grants Received
Berkovic SF, Jackson G, Petrou S, Reutens DC, Scheffer IE & Williams DA. 2002. Epilepsy: A collaborative research program from genome to patient. NH&MRC, Program Grant.
Bornstein JC. 2002. Behaviour of large networks of neurons in a functioning organ: a realistic computer based model of the enteric nervous system. ARC, Discovery - Project Grant.
Bornstein JC, Davies PJ & Bertrand PP. 2002. Properties and electrophysiology of the intrinsic nervous system. NH&MRC, Project Grant.
Ellis JA. 2002. Genetic determinants of adult height in the general population. University of Melbourne, Early Career Research Grant.
Ellis JA. 2002. The role of the aromatase gene in male height. J N Peters Bequest, Peters Fellowship.
Harrap SB & Di Nicolantonio R. 2002. Physiological genomic analysis of Lvm-1 - a genetic locus that determines left ventricular mass. NH&MRC, Project Grant.
Harrap SB, Wong ZYH & Ellis JA. 2002. Linkage and sequence analysis of a locus on the X chromosome that contributes to population variation in blood pressure. NH&MRC, Project Grant.
Wilkinson-Berka JLA. 2002. Does Cox-2 inhibition prevent angiogenesis in a rodent model of retinopathy of prematurity? Diabetes Australia, Research Grant.
Wilkinson-Berka JLA & Gilbert RE. 2002. Prevention of diabetic ocular neovascularization: anti-angiogenic effects of ZD6474. Astra Zeneca, Project Grant.
Wlodek ME & Moseley JM. 2002. Roles of PTHrP and calcium in placental and mammary function in perinatal growth restriction. NH&MRC, Project Grant.