Publications Report 2003
C1 - Journal Articles - Refereed
Baldwin J, Snow R, Gibala MJ, Garnham A, Howarth K & Febbraio MA. 2003. Glycogen availability does not affect the TCA cycle or TAN pools during prolonged, fatiguing exercise. Journal of Applied Physiology. 94:2181-2187.
Bian XC, Bornstein JC & Bertrand PP. 2003. Nicotinic transmission at functionally distinct synapses in descending reflex pathways of the rat colon. Neurogastroenterology and Motility. 15(2):161-171.
Carey AL, Lamont BJ, Andrikopoulos S, Koukoulas I, Proietto J & Febbraio MA. 2003. Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle following insulin stimulation. Biochemical and Biophysical Research Communications. 302:837-840.
Chen Z, Stephens TJ, Murthy S, Canny BJ, Hargreaves M, Witters LA, Kemp BE & McConell GK. 2003. Effect of exercise intensity on skeletal muscle AMPK signaling in humans. Diabetes. 52:2205-2212.
Clarke AL, Petrou S, Walsh Jr JV & Singer JJ. 2003. Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells. American Journal of Physiology - Cell Physiology. 284:C607-C619.
Cornish J, Callon KE, Mountjoy KG, Bava U, Lin JM, Myers DE, Naot D & Reid IR. 2003. α-Melanocyte-stimulating hormong is a novel regulator of bone. American Journal of Physiology - Endocrinology and Metabolism. 284:E1181-E1190.
Cui J, Hopper JL & Harrap SB. 2003. Antihypertensive treatments obscure familial contributions to blood pressure variation. Hypertension. 41:207-210.
Emptage NJ, Reid CA, Fine A & Bliss TVP. 2003. Optical Quantal Analysis reveals a presynaptic component of LTP at hippocampal schaffer-associated synapses. Neuron. 38:797-804.
Febbraio MA, Steensberg A, Starkie RL, McConell GK & Kingwell BA. 2003. Skeletal muscle interleukin-6 and tumor necrosis factor-α release in healthy subjects and patients with type 2 diabetes at rest and during exercise. Metabolism: Clinical and Experimental. 52(7):939-944.
Frauman AG, Fabiani ME, Hawkes DJ, Tikellis C, Johnston C & Wilkinson-Berka JLA. 2003. Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2) rat: effect of angiotensin-converting enzyme inhibition. International Journal of Biochemistry and Cell Biology. 35:973-983.
Harrap SB, Tzourio C, Cambien F, Poirier O, Raoux S, Chalmers J, Chapman N, Colman S, Leguennec S, MacMahon S, Neal B, Ohkubo T & Woodward M. 2003. The ACE Gene I/D Polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition. Hypertension. 42:297-303.
Huggins CE, Domenighetti AAM, Pedrazzini T, Pepe L & Delbridge LM. 2003. Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice. Journal of the Renin-Angiotensin-Aldosterone System. 4(3):186-190.
Kaczmarczyk S, Andrikopoulos S, Favaloro J, Domenighetti AAM, Dunn AR, Ernst M, Grail D, Fodero-Tavoletti MT, Huggins CE, Delbridge LM, Zajac JD & Proietto J. 2003. Threshold effects of glucose transporter-4 (GLUT-4) definiency on cardiac glucose uptake and development of hypertrophy. Journal of Molecular Endocrinology. 31:449-459.
Kelly DJ, Zhang Y, Hepper CL, Gow R, Jaworski K, Kemp BE, Wilkinson-Berka JLA & Gilbert RE. 2003. Protein kinase C β inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. Diabetes. 52:512-518.
Kingwell BA, Formosa M, Muhlmann M, Bradley S & McConell GK. 2003. Type 2 diabetic individuals have impaired leg blood flow responses to exercise. Diabetes Care. 26(3):899-904.
Macheda ML, Williams ED, Best JD, Wlodek ME & Rogers SD. 2003. Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland. Cell and Tissue Research. 311:91-97.
Moravski CJ, Skinner SL, Stubbs AJ, Sarlos S, Kelly DJ, Cooper ME, Gilbert RE & Wilkinson-Berka JLA. 2003. The renin-angiotensin system influences ocular endothelial cell proliferation in Diabetes. American Journal of Pathology. 162(1):151-160.
Morgan TO & Anderson A. 2003. Different drug classes have variable effects on blood pressure depending on the time of day. American Journal of Hypertension. 16(1):46-50.
Morgan TO & Anderson A. 2003. The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs. Journal of Clinical Hypertension. 5(1):53-57.
Nowson CA, Morgan TO & Gibbons C. 2003. Decreasing dietary sodium while following a self-selected potassium-rich diet reduces blood pressure. Journal of Nutrition. 133(12):4118-4123.
Plant DR, Gregorevic P, Warmington SA, Williams DA & Lynch GS. 2003. Endurance training adaptations modulate the redox-force relationship of rat isolated slow-twitch skeletal muscles. Clinical and Experimental Pharmacology and Physiology. 30:77-81.
Plant DR, Kearns CF, McKeever KH & Lynch GS. 2003. Therapeutic clenbuterol treatment does not alter Ca2+ sensitivity of permeabilized fast muscle fibres from exercise trained or untrained horses. Journal of Muscle Research and Cell Motility. 24:471-476.
Plant DR & Lynch GS. 2003. Depolarization-induced contraction and SR function in mechanically skinned muscle fibers from dystrophic mdx mice. American Journal of Physiology - Cell Physiology. 285(3):C522-C528.
Ritchie RH, Sun X, Bilszta JLC, Gulluyan LM & Dusting GJ. 2003. Cardioprotective actions of an N-terminal gragment of annexin-1 in rat myocardium in vitro. European Journal of Pharmacology. 461(2-3):171-179.
Rogers SD, Chandler JD, Clarke AL, Petrou S & Best JD. 2003. Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes. Biochemical and Biophysical Research Communications. 308(3):422-426.
Rong P, Campbell DJ & Skinner SL. 2003. Hypertension in the (mRen-2)27 rat is not explained by enhanced kinetics of transgenic Ren-2 renin. Hypertension. 42:523-527.
Sangkabutra T, Crankshaw DP, Schneider C, Fraser SF, Sostaric S, Mason KD, Burge C, Skinner SL, McMahon LP & McKenna MJ. 2003. Impaired K+ regulation contributes to exercise limitation in end-stage renal failure. Kidney International. 63:283-290.
Sarlos S, Rizkalla B, Moravski CJ, Cao Z, Cooper ME & Wilkinson-Berka JLA. 2003. Retinal angiogenesis is mediated by an interaction between the Angiotensin Type 2 receptor, VEGF, and Angiopoietin. American Journal of Pathology. 163(3):879-887.
Sinnayah P, Blair-West JR, McBurnie MI, McKinley M, Oldfield BJ, Rivier JE, Vale WW, Walker LL, Weisinger RS & Denton DA. 2003. The effect of urocortin on ingestive behaviours and brain Fos immunoreactivity in mice. European Journal of Neuroscience. 18(2):373-382.
Smart ML, Gu B, Panchal R, Wiley J, Cromer B, Williams DA & Petrou S. 2003. P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. Journal of Biological Chemistry. 278(10):8853-8860.
Stanton MP, Hengel PT, Southwell BR, Chow CW, Keck J, Hutson JM & Bornstein JC. 2003. Cholinergic transmission to colonic circular muscle of children with slow-transit constipation is unimpaired, but transmission via NK2 receptors is lacking. Neurogastroenterology and Motility. 15:669-678.
Thomas EA & Bornstein JC. 2003. Inhibitory cotransmission or after-hyperpolarizing potentials can regulate firing in recurrent networks with excitatory metabotropic transmission. Neuroscience. 120(2):333-352.
Trongtorsak P, Morgan TO & Delbridge LM. 2003. Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility. Journal of the Renin-Angiotensin-Aldosterone System. 4(4):213-219.
Wiley JS, Dao-Ung P, Li CP, Shemon AN, Gu B, Smart ML, Barden JA, Petrou S & Sluyter R. 2003. An Ile-568 to Asn Polymorphism prevents normal trafficking and function of the Human P2X7 receptor. Journal of Biological Chemistry. 278(19):17108-17113.
Wilkinson-Berka JLA, Alousis NS, Kelly DJ & Gilbert RE. 2003. COX-2 inhibtion and retinal angiogenesis in a mouse model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science. 44:974-979.
Wing LMH, Reid C, Ryan P, Beilin LJ, Brown MA, Jennings GLR, Johnston CI, McNeil JJM, MacDonald GJ, Marley JE, Morgan TO & West M. 2003. A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly. New England Journal of Medicine. 348:583-592.
Wlodek ME, Westcott KT, Serruto A, O'Dowd R, Wassef L, Ho PWM & Moseley JM. 2003. Impaired mammary function and parathyroid hormone-related protein during lactation in growth-restricted spontaneously hypertensive rats. Journal of Endocrinology. 178:233-245.
C2 - Unrefereed Journal Articles
Mifsud SA, Kelly DJ, Qi W, Zhang Y, Pollock C, Wilkinson-Berka JLA & Gilbert RE. 2003. Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy. Nephron Physiology. 95:83-91.
C3 - Unrefereed Letters or Notes
Ellis JA & Harrap SB. 2003. Tall stories: the devilish detail of genetic association studies. Clinical Endocrinology. 59(3):278-279.
Morgan TO. 2003. Renin, Angiotensin, Sodium and Organ Damage. Hypertension Research. 26(5):349-354.
C5 - Other Refereed Contributions to Refereed Journals
Bertrand PP. 2003. ATP and sensory transduction in the enteric nervous system. The Neuroscientist. 9(4):243-260.
Gilbert RE, Krum H, Wilkinson-Berka JLA & Kelly DJ. 2003. The renin-angiotensin system and the long-term complications of diabetes: pathophysiological and therapeutic considerations. Diabetic Medicine. 20:607-621.
Harrap SB. 2003. Where are all the blood-pressure genes? Lancet. 361:2149-2151.
Mulley JC, Scheffer IE, Petrou S & Berkovic SF. 2003. Channelopathies as a genetic cause of epilepsy. Current Opinion in Neurology. 16(2):171-176.
Reid CA, Bekkers JM & Clements JD. 2003. Presynaptic Ca2+ channels: a functional patchwork. Trends in Neurosciences. 26(12):683-687.
Roberts CT, Owens J, Carter AM, Harding JE, Austgulen R & Wlodek ME. 2003. Insulin-like growth factors and foetal programming - a workshop report. Placenta. 24:S72-S75.
Van Den Brink OWV, Delbridge LM, Rosenfeldt FL, Penny D, Esmore DS, Quick D, Kaye DM & Pepe S. 2003. Endogenous cardiac opioids: Enkephalins in adaptation and protection of the heart. Heart Lung and Circulation. 12:178-187.
F1 - Conference Publications - Full written paper - refereed
Dantas AM, Kemm RE & Weaver DA. 2003. Hypothesis testing as a core component of a virtual experiment. In D Lassner & C McNaught (eds), Proceedings of Ed-Media 2003 World Conference on Educational Multimedia, Hypermedia and Telecommunications. 2328-2335. Norfolk, United States of America: Association for the Advancement of Computing in Education.
Dantas AM, Kemm RE & Weaver DA. 2003. Using QuickTime in a virtual experiment to present data for analysis and videos of procedures. In NS Smythe (ed), Proceedings of the Apple University Consortium Conference. 6.1-13. Sydney, Australia: Apple Computer Australia.
Wlodek ME, Ping SE, Kennedy GE, Kirk J, Judd TS & Keppell M. 2003. Developments in Authentic Learning: A Woman's Reproductive Life Cycle. In D Lassner & C McNaught (eds), Proceedings of ED-MEDIA 2003 World Conference on Educational Multimedia, Hypermedia & Telecommunications. 1 : 1431-1438. Norfolk, Va, United States of America: Association for the Advancement of Computing in Education (AACE).
Q8 - Research in Progress (RIP)
Bertrand PP. 2003. Sensory transduction mechanisms in the intestine: Integration of modalities.
Bertrand PP. 2003. Steroid regulation of serotonergic transmission in mouse CNS.
Bertrand PP. 2003. The neural control of serotonin release from intestinal enterochromaffin (EC) cells.
Delbridge LM, Di Nicolantonio R, Smyth G & Scott H. 2003. Gene expression profiling in the hypertrophic heart.
Delbridge LM, Harrap SB, Di Nicolantonio R, Davis G & Hiranyachattada S. 2003. Angiotensin and genetic cardiac hypertrophy.
Delbridge LM & Pedrazzini T. 2003. Growth factor regulation of cardiomyocyte growth signalling: transcriptome profiling, transdifferentiation and MAPK cascades.
Delbridge LM, Pepe S & McLennan P. 2003. Do membrane lipids modulate ischemic vulnerability in genetic cardiac hypertrophy?
Delbridge LM & Ritchie R. 2003. Role of reactive oxygen species in mediating structural and functional damage in cardiac hypertrophy.
Di Nicolantonio R, Delbridge LM & Harrap SB. 2003. Differential gene expression in experimental cardiac hypertrophy.
Di Nicolantonio R & Harrap SB. 2003. Physiological genomics of the Lvm-1 chromosomal locus controlling cardiac growth.
Di Nicolantonio R & Yamori Y. 2003. Dietary interventions in cardiovascular and diabetic disease in indigenous populations.
Ellis JA, Abramson M & Matheson M. 2003. Genetic and environmental risk factors for respiratory disease.
Ellis JA & Harrap SB. 2003. A paradigm of genomic discovery - an investigation of the allelic architecture of height.
Ellis JA & Harrap SB. 2003. The role of sex-steroid relates genes in cardiovascular risk.
Ellis JA, Harrap SB, Sinclair RD & Harrison SC. 2003. Genetic analysis of female pattern baldness.
Lynch GS, Woods MG & Wiesenfeld D. 2003. Human masseter muscle structure and function in subjects with different underlying vertical facial patterns.
McConell GK, Canny B, Hargreaves M, Kingwell BA, Kemp BE & Chen Z. 2003. Glucose uptake during exercise: important role of AMP-activated protein kinase and nitric oxide.
McConell GK, MacAulay L, Cameron-Smith D & Wadley GD. 2003. Is nitric oxide production during exercise required for increased post-exercise mitochondrial biogenesis?
Williams DA & Reid CA. 2003. Calcium signalling in neurons of the central nervous system.
Wlodek ME & Moseley JM. 2003. Role of PTHrP in placental and mammary function in models of perinatal growth restrictions.
Wlodek ME & Nicholas KR. 2003. Mammary programming of growth.
Wlodek ME, Owens J & Cooney G. 2003. Placental and mammary programming of growth and Syndrome X.
Wlodek ME & Rice GE. 2003. Apoptosis in normal and complicated human pregnancies.
Wong ZYH, Harrap SB & Ellis JA. 2003. Linkage and sequence analysis of a locus on the X chromosome that contributes to population variation in blood pressure.
Q9 - Substantial Grants Received
Barrett GL & Vaux D. 2003. How does the p75 neurotrophin receptor transmit both pro-survival and pro-apoptotic signals in neurons? NH&MRC, Project Grant.
Bertrand PP. 2003. Brain Slice Recording. NH&MRCMelbourne University, University Research Infrastructure Grant.
Bornstein JC. 2003. Computational models of motor patterns in the intestines. Victorian Partnership for Advanced Computing, Expertise Programs Grant.
Bornstein JC, Sjovall H & Davies PJ. 2003. Neural mechanisms mediating hypersecretion and motility patterns induced by enterotoxins. NH&MRC, Project Grant.
De Iongh R & Wlodek ME. 2003. Real-time quantitative PCR (Q-PCR) facility for multi-user molecular biology laboratory. NH&MRC, Equipment Grant.
Delbridge LM, Pepe S & McLennan P. 2003. Do membrane lipids modulate ischemic vulnerability in genetic cardiac hypertrophy? National Heart Foundation, Grand-in-Aid.
Harrap SB. 2003. DNA Analysis Platform. University of Melbourne, University Research Infrastructure Grant.
Lynch GS. 2003. Functional roles of utrophin and dystrophin in animal models of muscular dystrophy. Muscular Dystrophy Association USA, International Competitive.
Lynch GS. 2003. Growth factor therapy for improving muscle function in Muscular Dystrophy. Muscular Dystrophy Association USA, International Competitive.
Lynch GS. 2003. Novel role of Sildenafil in improving muscle repair and function following injury with application to the development of treatments for Muscular Dystrophy. Pfizer Pharmaceuticals Group USA, Viagra (sildenafil citrate) Research Grants Program.
McConell GK, Canny B & Hargreaves M. 2003. Glucose uptake during exercise: important role of AMP-activated protein kinase and nitric oxide. NH&MRC, Project Grant.
Pepe S & Delbridge LM. 2003. Opiod metabolism in human heart. NH&MRC, Project Grant.
Plant DR. 2003. Novel therapies to treat muscle wasting in muscular dystrophy. University of Melbourne, Early Career Researcher Grant Scheme.
Reid CA. 2003. Mechanisms underlying short- and long-term plasticity at the mossy fibre->CA3 synapse in the hippocampus. NH&MRC, Project Grant.
Reid CA. 2003. Mechanisms underlying synaptic plasticity in the central nervous system. University of Melbourne, Early Career Researcher Grant Scheme.
Smith G, Scott H, Di Nicolantonio R & Delbridge LM. 2003. Statistical issues in microarray data analysis. NH&MRC, Project Grant.
Thomas EA. 2003. Dynamics of slow synaptic transmission. University of Melbourne, Early Career Researcher Grants Scheme.
Wilkinson-Berka JLA. 2003. Evaluation of antisense therapies in mice with retinopathy of prematurity. Novartis, Switzerland, Commercial grant.
Wilkinson-Berka JLA. 2003. The anti-angiogenic effects of valsartan in a rodent model of retinopathy of prematurity. Novartis Pharma, Switzerland, Commercial.
Williams DA, Petrou S, Paolini AG, Reutens DC & Jackson G. 2003. Brain Slice Macroscopic Imaging and Electrophysiology Recording System. Australian Research Council, Linkage Infrastructure Equipment and Facilities grant.
Wong ZYH & Harrap SB. 2003. Linkage and association analyses of a locus on chromosome 4 that contributes to population variation in HDL. NH&MRC, Project Grant.
R11 - Thesis Passed for Higher Degrees
McTaggart SJ. 2003. Albumin endocytosis in renal proximal tubule cells.
Mifsud SA. 2003. The pathogenesis of diabetic and hypertensive nephropathy: interventional studies in the transgenic m(Ren-2)27 rat.
R12 - Thesis in Progress for Higher Degrees
Beitzel F. 2003. Improving muscle repair and function in the frail elderly following injury.
Berg RS. 2003. Role of Amp Kinase and Nitric Oxide synthase in glucose uptake during exercise in skeletal muscle.
Dantas AM. 2003. Cellular mechanism of actions of peptide hormones in the kidney.
Harcourt LJ. 2003. Assessing the effectiveness of various pharmacological therapies for treating muscular dystrophy.
Huggins CE. 2003. does dietary omega-3 fat supplementation protect genetically enlarged hearts against ischemic injury?
Monro R. 2003. Calcium channel subtypes involved in Neurotransmitter release in the Enteric Nervous System.
O'Dowd RA. 2003. The roles of PTHrP in mammary function and perinatal growth.
Ong LGT. 2003. Structural and functional studies in a transgenic rat model of diabetic retinopathy.
Ping SE. 2003. Oestrogen: a trophic factor in cholinergic basal forebrain neurons.
Ryall JG. 2003. Age-related changes in cardiac and skeletal muscle following b2-agonist administration.
Sarlos S. 2003. Involvement of the renin-angiostensin system and related growth factors in angiogenesis: studies in developing retina and ischaemic ocular pathologies.
Schertzer JD. 2003. Skeletal and cardiac muscle pathology: From molecule to function.
Stupka N. 2003. The contribution of the calcineurin signal transduction pathway to muscle regeneration in Duchenne muscular dystrophy.
Zentner D. 2003. Longitudinal studies of cardiac and haemodynamic physiology in relation to female sex hormones.